Primary aldosteronism

Adrenal vein sampling lateralization despite mineralocorticoid receptor antagonists exposure in primary aldosteronism

**Context:** Many antihypertensive medications modulate the renin-angiotensin-aldosterone system, possibly skewing the diagnosis and subtyping of primary aldosteronism (PA). Particularly, mineralocorticoid receptor antagonists (MRA) might raise renin …

Primary aldosteronism

A pragmatic discussion of the diagnosis and treatment of primary aldosteronism.

Discordance between imaging and immunohistochemistry in unilateral primary aldosteronism

**OBJECTIVE:** Correct subtyping of primary aldosteronism (PA) is essential for good surgical outcomes. Adrenal vein sampling (AVS) and/or computed tomography (CT) are used for PA subclassification. Clinical and/or biochemical improvement after …

Primary aldosteronism in the primary care clinic: rife or rare?

Aldosterone synthase promoter polymorphism and cardiovascular phenotypes in a large, multiethnic population-based study

**BACKGROUND:** A single-nucleotide polymorphism in the aldosterone synthase gene (CYP11B2) promoter [-344C/T, rs1799998] has been reported to associate with cardiovascular phenotypes. **METHODS:** The Dallas Heart Study is a large, multiethnic …