Extracellular Vesicles

For what factors should we normalize urinary extracellular mRNA biomarkers?

mRNA is a critical biomolecule involved in the manifestation of the genetic code into functional protein molecules. Its critical role in the central dogma has made it a key target in many studies to determine biomarkers and drug targets for numerous …

Minimal information for studies of extracellular vesicles 2018 (MISEV2018), a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines

Updated guidelines for the reporting of experiments involving extracellular vesicles.

Clinical research using extracellular vesicles, insights from the International Society for Extracellular Vesicles 2018 Annual Meeting

Clinical research involving extracellular vesicles.

Human urinary mRNA as a biomarker of cardiovascular disease

Analysis of the relationship between gene expression in the human renal cortex and urinary extracellular vesicles, as well as a study of intentional modulation of the renin-angiotensin-aldosterone system in humans with attention to corresponding changes in mRNA transcript abundance in the urine supernatant.

Summary of the ISEV workshop on extracellular vesicles as disease biomarkers, held in Birmingham, UK, during December 2017

Our and others' research presented at the 2018 International Society for Extracellular Vesicles' Biomarkers Workshop, Birmingham, UK.

EV-TRACK: transparent reporting and centralizing knowledge in extracellular vesicle research

We argue that the field of extracellular vesicle (EV) biology needs more transparent reporting to facilitate interpretation and replication of experiments. To achieve this, we describe EV-TRACK, a crowdsourcing knowledgebase (http://evtrack.org) that …

Extracellular Vesicles